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2006 - 2010

414. D. B. Guthrie, S. J. Geib, D. P. Curran, Radical and Heck Cyclizations of Diastereomeric o-Haloanilide Atropisomers, J. Am. Chem. Soc., 2010, 133, 115-122. doi: 10.1021/ja108795x

413. J. Monot, A. Solovyev, H. Bonin-Dubarle, É. Derat, D. P. Curran, M. Robert, L. Fensterbank, M. Malacria, E. Lacôte, Generation and Reactions of an Unsubstituted N-Heterocyclic Carbene Boryl Anion, Angew. Chem. Int. Ed., 2010, 49, 9166-9169. doi: 10.1002/anie.201004215

412. Y. Lu, S. J. Geib, K. Damodaran, B. Sui, Z. Zhang, D. P. Curran, W. Zhang, Fluorous Diasteromeric Mixture Synthesis (FDMS) of Hydantoin-fused Hexahydrochromeno[4,3-b] pyrroles, Chem. Commun., 2010, 46, 7578-7580. doi: 10.1039/c0cc01967d

411. M. Makhlouf Brahmi, J. Monot, M. Desage-El Murr, D. P. Curran, L. Fensterbank, E. Lacôte, M. Malacria, Preparation of NHC Borane Complexes by Lewis Base Exchange with Amine- and Phosphine-Boranes, J. Org. Chem., 2010, 75, 6983-6985. doi: 10.1021/jo101301d

410. A. Solovyev, Q. Chu, S. J. Geib, L. Fensterbank, M. Malacria, E. Lacôte, D. P. Curran, Substitution Reactions of Tetracoordinate Boron: Synthesis of N-Heterocyclic Carbene Boranes with Boron-Heteroatom Bonds, J. Am. Chem. Soc., 2010, 132, 15072-15080. doi: 10.1021/ja107025y

409. J. Monot, L. Fensterbank, M. Malacria, E. Lacôte, S. J. Geib, D. P. Curran, CAAC Boranes. Synthesis and characterization of cyclic (alkyl) (amino) carbene borane complexes from BF3 and BH3, Beilstein J. Org. Chem., 2010, 6, 709-712. doi: 10.3762/bjoc.6.82

408. D. C. Harrowven, D. P. Curran, S. L. Kostiuk, I. L. Wallis-Guy, S. Whiting, K. J. Stenning, B. Tang, E. Packard, L. Nanson, Potassium Carbonate-Silica: A Highly Effective Stationary Phase for the Chromatographic Removal of Organotin Impurities, Chem. Commun., 2010, 46, 6335-6337. doi: 10.1039/C0CC01328E

407. A. Bruch, A. Ambrosius, R. Fröhlich, A. Studer, D. B. Guthrie, H. Zhang, D. P. Curran, Memory of Axial Chirality in Aryl Radical Phosphanylations, J. Am. Chem. Soc., 2010, 132, 11452-11454. doi: 10.1021/ja105070k

406. K. Nozaki, Y. Aramaki, M. Yamashita, S.-H. Ueng, M. Malacria, E. Lacôte, D. P. Curran, Boryltrihydroborate: Synthesis, Structure, and Reactivity as a Reductant in Ionic, Organometallic, and Radical Reactions, J. Am. Chem. Soc., 2010, 132, 11449-11451. doi: 10.1021/ja105277u

405. W. Zhu, M. Jiménez, W.-H. Jung, D. P. Camarco, R. Balachandran, A. Vogt, B. W. Day, D. P. Curran, Streamlined Syntheses of (–)-Dictyostatin, 16-Desmethyl-25,26-dihydrodictyostatin, and 6-epi-16-Desmethyl-25,26-dihydrodictyostatin, J. Am. Chem. Soc., 2010, 132, 9175. doi: 10.1021/ja103537u. PMCID: PMC2903049

404. S.-H. Ueng, L. Fensterbank, E. Lacôte, M. Malacria, D. P. Curran, Radical Deoxygenation of Xanthates and Related Functional Groups with New Minimalist N-Heterocyclic Carbene Boranes, Org. Lett., 2010, 12, 3002. doi: 10.1021/ol101015m

403. A. Solovyev, S.-H. Ueng, J. Monot, L. Fensterbank, M. Malacria, E. Lacôte, D. P. Curran, Estimated Rate Constants for Hydrogen Abstraction from N-Heterocyclic Carbene–Borane Complexes by an Alkyl Radical, Org. Lett., 2010, 12, 2998. doi: 10.1021/ol101014q

402. B. Sui, E. A.-H. Yeh, D. P. Curran, Assignment of the Structure of Petrocortyne A by Mixture Synthesis of Four Candidate Stereoisomers, J. Org. Chem., 2010, 75, 2942. doi: 10.1021/jo100115h. PMCID: PMC2871111

401. M.-A. Tehfe, M. Makhlouf Brahmi, J.-P. Fouassier, D. P. Curran, M. Malacria, L. Fensterbank, E. Lacôte, J. Lalevée, N-Heterocyclic Carbenes-Borane Complexes: A New Class of Initiators for Radical Photopolymerization, Macromolecules, 2010, 43, 2261. doi: 10.1021/ma902492q

400. J. C. Walton, M. M. Brahmi, L. Festerbank, E. Lacôte, M. Malacria, Q. Chu, S.-H. Ueng, A. Solovyev, D. P. Curran, EPR Studies of the Generation, Structure, and Reactivity of N-Heterocyclic Carbene Borane Radicals, J. Am. Chem. Soc., 2010, 132, 2350. doi: 10.1021/ja909502q

399. K. Zhang, D. P. Curran, Fluorous Mixture Synthesis of Four Stereoisomers of the C21-C40 Fragment of Tetrafibricin, Synlett, 2010, 667. doi: 10.1055/s-0029-1219376

398. X. Li, D. P. Curran, Diverging Chemoselective Reactions of Separable Amide Rotational Isomers, Org. Lett., 2010, 12, 612. doi: 10.1021/ol902808m

397. L. Wang, C. Cai, D. P. Curran, W. Zhang, Enantioselective α-Chlorination of Aldehydes with Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst, Synlett, 2010, 433. doi: 10.1055/s-0029-1219198

396. D. B. Guthrie, S. J. Geib, D. P. Curran, Synthesis of Highly Enantioenriched 3,4-Dihydroquinolin-2-ones by 6-Exo-trig Radical Cyclizations of Axially Chiral α-Halo-ortho-alkenyl Anilides, J. Am. Chem. Soc., 2009, 131, 15492. doi: 10.1021/ja9066282

395. J. Monot, M. Makhlouf Brahmi, S.-H. Ueng, C. Robert, M. Desage-El Murr, D. P. Curran, M. Malacria, L. Fensterbank, E. Lacôte, Suzuki-Miyaura Coupling of NHC-Boranes: A New Addition to the C–C Coupling Toolbox, Org. Lett., 2009, 11, 4914. doi: 10.1021/ol902012c

394. K. Damodaran, S. D. Nielsen, S. J. Geib, W. Zhang, Y. Lu, D. P. Curran, Aryl-Csp3 Bond Rotation Barriers of 2-Aryl Perhydropyrrolo[3,4-c]pyrrole-1,3-diones, J. Org. Chem., 2009, 74, 5481. doi: 10.1021/jo901123c

393. A. L. Mandel, V. Bellosta, D. P. Curran, J. Cossy, A Versatile Route to the Tulearin Class of Macrolactones: Synthesis of a Stereoisomer of Tulearin A, Org. Lett., 2009, 11, 3285. doi: 10.1021/ol900936t

392. S.-H. Ueng, A. Solovyev, X. Yuan, S. J. Geib, L. Fensterbank, E. Lacôte, M. Malacria, M. Newcomb, J. C. Walton, D. P. Curran, N-Heterocyclic Carbene Boryl Radicals: A New Class of Boron-Centered Radical, J. Amer. Chem. Soc., 2009, 131, 11256. doi: 10.1021/ja904103x

391. S. Werner, S. D. Nielsen, P. Wipf, D. M. Turner, P. G. Chambers, S. J. Geib, D. P. Curran, W. Zhang, Fluorous Parallel Synthesis of a Piperazinedion-Fused Tricyclic Compound Library, J. Comb. Chem., 2009, 11, 452. doi: 10.1021/cc900003q

390. Q. Chu, M. Makhlouf Brahmi, A. Solovyev, S.-H. Ueng, D. P. Curran, M.Malacria, L. Fensterbank, E. Lacôte, Ionic and Organometallic Reductions with N-Heterocyclic Carbene Boranes, Chem. Eur. J., 2009, 15, 12937. doi: 10.1002/chem.200902450.

389. V. Gudipati, R. Bajpai, D. P. Curran, Sulfanylation of 1,3- Dithiane Anions by 5-(Alkylsulfanyl)-1-Phenyltertrazoles, Collect. Czech. Chem. Commun., 2009, 74, 771. doi: 10.1135/cccc2008195

388. D. B. Guthrie, K. Damodaran, D. P. Curran, P. Wilson, A. J. Clark, Bond Rotation Dynamics of N-Cycloalkenyl-N-benzyl a-Haloacetamide Derivatives, J. Org. Chem., 2009, 74, 4262. doi: 10.1021/jo900491w

387. A. G. Sancho, X. Wang, B. Sui, D. P. Curran, Comparison of the Relative Reactivities of the Triisopropylsilyl Group With Two Fluorous Analogs, Adv. Synth. Catal., 2009, 351, 1035. doi: 10.1002/adsc.200900061

386. D. P. Curran and B. Sui, A “Shortcut” Mosher Ester Method to Assign Configurations of Stereocenters in Nearly Symmetric Environments. Fluorous Mixture Synthesis and Structure Assignment of Petrocortyne A, J. Amer. Chem. Soc. , 2009, 131, 5411. doi: 10.1021/ja900849f

385. F. Zhang, W. Zhang, Y. Zhang, D. P. Curran, G. Liu, Synthesis and Applications of a Light-Fluorous Glycosyl Donor, J. Org. Chem., 2009, 74, 2594. doi: 10.1021/jo9000993

384. V. Montanari, M. S. Yu, D. P. Curran, Thieme Chemistry Journal Awardees – Where are They Now? Catalytic Transport with an Amine Carrier in a Fluorous Triphasic Reaction, Synlett, 2009, 4, 554. doi: 10.1055/s-0028-1087916

383. D. B. Guthrie and D. P. Curran, Asymmetric Radical and Anionic Cyclizations of Axially Chiral Carbamates, Org. Lett., 2009, 11, 249. doi: 10.1021/ol802616u

382. D. P. Curran, Fluorous Mixture Synthesis of Natural Product Stereoisomer Libraries, Anal. Quimica, 2008, Supplement, 10.

381. I. Ryu, H. Matsubara, H. Nakamura, D. P. Curran, Phase-Vanishing Methods Based on Fluorous Phase Screen: A Simple Way for Efficient Execution of Organic Synthesis, The Chemical Record, 2008, 8, 351. doi: 10.1002/tcr.20161

380. D. P. Curran, Synthetic Approaches to Homocamptothecin Antitumor Agents, C. R. Chimie, 2008, 11, 1574. doi: 10.1016/j.crci.2008.10.002

379. M. Osipov, Q. Chu, S. J. Geib, D. P. Curran, S. G. Weber, Synthesis of Deep-Cavity Calix[4]arenes as Molecular Recognition Scaffolds, Beilstein J. Org. Chem. 2008, 4:36. doi: 10.3762/bjoc.4.36

378. J. L. Eiseman, L. Bai, W.-H. Jung, G. Moura-Letts, B. W. Day, D. P. Curran, Improved Synthesis of 6-epi-Dictyostatin and Antitumor Efficacy in Mice Bearing MDA-MB231 Human Breast Cancer Xenografts, J. Med. Chem. 2008, 51, 6650. doi: 10.1021/jm800979v

377. D. P. Curran, Fluorous Tags Unstick Messy Chemical Biology Problems, Science, 2008, 321, 1645. doi: 10.1126/science.1158721

376. D. P. Curran, Fluorous Chemistry in Pittsburgh: 1996-2008, J. Flourine Chem., 2008, 129, 898. doi: 10.1016/j.jfluchem.2008.05.025

375. S.-H. Ueng, M. Makhlouf Brahmi, E. Derat, L. Fensterbank, E. Lacôte, M. Malacria, D. P. Curran, Complexes of Borane and N-Heterocyclic Carbenes: A New Class of Radical Hydrogen Atom Donor, J. Am. Chem. Soc. 2008, 130, 10082. doi: 10.1021/ja804150k

374. Q. Chu, C. Henry, and D. P. Curran, Second-Generation Tags for Fluorous Chemistry Exemplified with a New Fluorous Mitsunobu Reagent, Org. Lett. 2008, 10, 2453. doi: 10.1021/ol800750q

373. D. P. Curran, D. B. Guthrie, and S. J. Geib, How Do Analogous α-Chloroenamides and α-Iodoenamides Give Different Product Distributions in 5-Endo Radical Cyclizations? J. Amer. Chem. Soc. 2008, 130, 8437. doi: 10.1021/ja8012962

372. W. C. Zamboni, L. L. Jung, S. Strychor, E. Joseph, B. A. Zamboni, S. A. Fetteman, B. J. Sidone, T. G. Burke, D. P. Curran, and J. L. Eiseman, Plasma and Tissue Disposition of Non-liposomal DB-67 and liposomal DB-67 in C.B-17 SCID Mice, Invest. New Drugs, 2008. doi:10.1007/s10637-007-9109-9

371. Q. Chu, M. S. Yu, and D. P. Curran, CBS Reductions with a Fluorous Prolinol Immobilized in a Hydrofluoroether Solvent, Org. Lett. 2008, 10, 749. doi: 10.1021/ol702778v

370. B. S. Raccor, A. Vogt, R. P. Sikorski, C. Madiraju, R. Balanchandran, K. Montgomery, Y. Shin, Y. Fukui, W.-H. Jung, D. P. Curran, and B. W. Day, Cell-Based and Biochemical Structure-Activity Analyses Analogs of the Microtubule Stabilizer Dictyostatin, Mol. Pharmacol. 2008, 73, 718. doi:10.1124/mol.107.042598

369. W.-H. Jung, S. Guyenne, C. Riesco-Fagundo, J. Mancuso, S. Nakamura, and D. P. Curran, Confirmation of the Stereostructure of (+)-Cytostatin by Fluorous Mixture Synthesis of Four Candidate Stereoisomers, Angew. Chem. Int. Ed. 2008, 47, 1130. doi:10.1002/anie.200704893

368. T. Tonoi, W. Zhang, D. P. Curran, and K. Mikami, Fluorous “Racemic” Mixture Synthesis: Polysaccharide-Based Chiral Columns for Simultaneious Demix and Enantioseparation of Racemic Fluorous Tagged Compounds, Chirality 2008, 20, 597. doi:10.1002/chir.20487

367. T. Cohen, H. Gibney, R. Ivanov, E. A.-H. Yeh, I. Marek, and D. P. Curran, Intramolecular Carbozincation of Unactivated Alkenes Occurs through a Zinc Radical Transfer Mechanism, J. Am. Chem. Soc. 2007, 129, 15405. doi: 10.1021/ja076554k

366. C. del Pozo, A. I. Keller, T. Nagashima, and D. P. Curran, Amide Bond Formation with a New Fluorous Carbodiimide: Separation by Reverse Fluorous Solid-Phase Extraction, Org. Lett. 2007, 9, 4167. doi:10.1021/ol701631m

365. R. Bajpai, F. Yang, and D. P. Curran, On the Structure of the Phytophthora a1 Mating Hormone: Synthesis and Comparison of Four Candidate Stereoisomers, Tetrahedron Lett. 2007, 48, 7965. doi:10.1016/j.tetlet.2007.09.054

364. W.-H. Jung, C. Harrison, Y. Shin, J.-H. Fournier, R. Balachandran, B. S. Raccor, R. P. Sikorski, A. Vogt, D. P. Curran, and B. W. Day, Total Synthesis and Biological Evaluation of C16 Analogs of (–)-Dictyostatin, J. Med. Chem. 2007, 50, 2951. doi:10.1021/jm061385k

363. Q. Chu, M. S. Yu, and D. P. Curran, New Fluorous/Organic Biphasic Systems Achieved by Solvent Tuning, Tetrahedron 2007, 63, 9890. doi:10.1016/j.tet.2007.06.092

362. Y. Shin, J.-H. Fournier, A. Brückner, C. Madiraju, R. Balachandran, B. S. Raccor, M. C. Edler, E. Hamel, R. P. Sikorski, A. Vogt, B. W. Day, and D. P. Curran, Synthesis and Biological Evaluation of (–)-Dictyostatin and Stereoisomers, Tetrahedron 2007, 63, 8537. doi:10.1016/j.tet.2007.05.033

361. X. Wang, S. G. Nelson, and D. P. Curran, The Azido Acid Approach to β-Peptides: Parallel Synthesis of a Tri-β-Peptide Library by Fluorous Tagging, Tetrahedron 2007, 63, 6141. doi:10.1016/j.tet.2007.03.034

360. A. J. B. Lapierre, S. J. Geib, and D. P. Curran, Low-Temperature Heck Reactions of Axially Chiral o-Iodoacrylanilides Occur with Chirality Transfer: Implications for Catalytic Asymmetric Heck Reactions, J. Am. Chem Soc. 2007, 129, 494. doi:10.1021/ja067790i

359. G. Moura-Letts and D. P. Curran, Selective Synthesis of (2Z,4E)-Dienyl Esters by Ene–Diene Cross Metathesis, Org. Lett. 2007, 9, 5. doi:10.1021/ol062017d

358. Q. Chu, W. Zhang, and D. P. Curran, A Recyclable Fluorous Organocatalyst for Diels–Alder Reactions, Tetrahedron Lett. 2006, 47, 9287. doi:10.1016/j.tetlet.2006.10.101

357. E. Hamel, B. W. Day, J. H. Miller, M. K. Jung, P. T. Northcote, A. K. Ghosh, D. P. Curran, M. Cushman, K. C. Nicolaou, I. Paterson, and E. J. Sorensen, Synergistic Effects of Peloruside A and Laulimalide with Taxoid Site Drugs, but Not with Each Other, on Tubulin Assembly, Mol. Pharmacol. 2006, 70, 1555. doi:10.1124/mol.106.027847

356. D. P. Curran and A. I. Keller, Radical Additions of Aryl Iodides to Arenes Are Facilitated by Oxidative Rearomatization with Dioxygen, J. Am. Chem. Soc. 2006, 128, 13706. doi:10.1021/ja066077q

355. W. Zhang and D. P. Curran, Synthetic Applications of Fluorous Solid-Phase Extraction (F-SPE), Tetrahedron 2006, 62, 11837. doi:10.1016/j.tet.2006.08.051

354. F. Yang, J. J. Newsome, and D. P. Curran, Structure Assignment of Lagunapyrone B by Fluorous Mixture Synthesis of Four Candidate Stereoisomers, J. Am. Chem. Soc. 2006, 128, 14200. doi:10.1021/ja064812s

353. D. P. Curran, R. Bajpai, and E. Sanger, Purification of Fluorous Mitsunobu Reactions by Liquid-Liquid Extraction, Adv. Synth. Catal. 2006, 348, 1621. doi:10.1002/adsc.200606187

352. R. S. Tangirala, S. Antony, K. Agama, Y. Pommier, B. D. Anderson, R. Bevins, and D. P. Curran, Synthesis and Biological Assays of E-Ring Analogs of Camptothecin and Homocamptothecin, Bioorg. Med. Chem. 2006, 14, 6202. doi:10.1016/j.bmc.2006.05.073

351. D. P. Curran, Q. Zhang, H. Lu, and V. Gudipati, On the Proof and Disproof of Natural Product Stereostrucures: Characterization and Analysis of a Twenty-Eight Member Stereoisomer Library of Murisolins and their Mosher Ester Derivatives, J. Am. Chem. Soc. 2006, 128, 9943. doi:10.1021/ja062469l

350. D. P. Curran, Q. Zhang, C. Richard, H. Lu, V. Gudipati, and C. Wilcox, Total Synthesis of a 28-Member Stereoisomer Library of Murisolins, J. Am. Chem. Soc. 2006, 128, 9561. doi:10.1021/ja061801q

349. D. P. Curran and C. Ogoe, A New Fluorous Methoxymethyl (FMOM) Protecting Group for Alcohols, QSAR & Comb. Sci. 2006, 25, 732. doi:10.1002/qsar.200640047

348. M. Matsugi, K. Yamanaka, I. Inomata, N. Takekoshi, M. Hasegawa, and D. P. Curran, Synthesis of Fluorous-FMOC Reagents and Purification of Protected Dipeptides with Fluorous Solid Phase Extraction, QSAR & Comb. Sci. 2006, 25, 713. doi:10.1002/qsar.200640044

347. D. P. Curran and T. R. Turner, Do α-Acyloxy and α-Alkoxycarbonyloxy Radicals Fragment to Form Acyl and Alkoxycarbonyl Radicals? Beilstein J. Org. Chem. 2006, 2:10. doi:10.1186/1860-5397-2-10

346. D. P. Curran, K. Mikami, and V. A. Soloshonok, Current Frontiers of Fluoroorganic Chemistry and Recent Adances in Fluorous Chemistry, J. Fluorine Chem. 2006, 127, 454. doi:10.1016/j.jfluchem.2006.01.005

345. V. Gudipati, D. P. Curran, and C. S. Wilcox, Solution-Phase Parallel Synthesis with Oligoethylene Glycol Sorting Tags. Preparation of All Four Stereoisomers of the Hydroxybutenolide Fragment of Murisolin and Related Acetogenins, J. Org. Chem. 2006, 71, 3599. doi:10.1021/jo060217x

344. Y. Fukui, A. M. Brückner, Y. Shin, R. Balachandran, B. W. Day, and D. P. Curran, Fluorous Mixture Synthesis of ()-Dictyostatin and Three Stereoisomers, Org. Lett. 2006, 8, 301. doi:10.1021/ol0526827

343. W. Zhang, Y. Lu, C. H.-T. Chen, D. P. Curran, and S. Geib, Fluorous Synthesis of Hydantoin-, Piperazinedione-, and Benzodiazepinedxione-Fused Tricyclic and Tetracyclic Ring Systems, Eur. J. Org. Chem. 2006, 2055. doi:10.1002/ejoc.200600077

342. G. Zhu, F. Yang, R. Balachandran, P. Höök, R. B. Vallee, D. P. Curran, and B. W. Day, Synthesis and Biological Evaluation of Purealin and Analogues as Cytoplasmic Dynein Heavy Chain Inhibitors, J. Med. Chem. 2006, 49, 2063. doi:10.1021/jm051030l

341. D. P. Curran, G. Moura-Letts, and M. Pohlman, Solution-Phase Mixture Synthesis with Fluorous Tagging En Route: Total Synthesis of an Eight-Member Stereoisomer Library of Passifloricins, Angew. Chem. Int. Ed. 2006, 45, 2423. doi:10.1002/anie.200600041

340. D. P. Curran, Organic Synthesis with Light-Fluorous Reagents, Reactants, Catalysts, and Scavengers, Aldrichimica Acta 2006, 39, 3. http://www.sigmaaldrich.com/aldrich/acta/al_acta_39_1.pdf